The first season of First Wave contained 22 episodes.
- “Subject 117"
- "Crazy Eddie"
- "Mata Hari"
- "Hypnotic"
- "Elixir"
- "Speaking in Tongues"
- "Lungfish"
- "Book of Shadows"
- "Joshua"
- "Marker 262"
- "Motel California"
- "Breeding Ground"
- "Blue Agave"
- "Cul-De-Sac"
- "The Box"
- "The Undesirables"
- "Second Wave"
- "Blind Witness"
- "Deluge"
- "Melody"
- "The Aftertime"
- "The Decision"